تفاعل #927225

معادلة التفاعل

water

triethylamine

para-acetylaminophenol

lauroyl chloride

→

Lauroyl [4-(N-acetylamino)]phenol

المردود 12.0%

المذيبات

DMF

ظروف التفاعل

المعالجة

1. 1
   أخرىthe product precipitates
2. 2
   غسيلIt is washed with heptane
3. 3
   أخرىdried under vacuum

الإجراء التجريبي

An equivalent amount in moles of para-acetylaminophenol and lauroyl chloride are placed in contact at 0° C. in DMF (dilution=15%) in the presence of one molar equivalent of triethylamine. The mixture is allowed to warm to room temperature with stirring and the reaction medium is then poured into water and the product precipitates. It is washed with heptane and then dried under vacuum. The yield is 12%. The elemental analysis is in accordance with the structure.

المصدر