تفاعل #92676

معادلة التفاعل

3-(cyclohexylmethoxy)-5-methyl-2-nitropyridine

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3-(cyclohexylmethoxy)-5-methylpyridin-2-amine

المردود 87.1%

المذيبات

THF

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe reaction mixture was filtered over Celite
2. 2
   أخرىthe solvent was then evaporated under reduced pressure

الإجراء التجريبي

To a solution of 1.8 g of 3-(cyclohexylmethoxy)-5-methyl-2-nitropyridine in 16 ml of THF was added 325 mg of 10% palladium-carbon (wet), followed by stirring for 3 hours under a hydrogen atmosphere. The reaction mixture was filtered over Celite and the solvent was then evaporated under reduced pressure to obtain 1.38 g of 3-(cyclohexylmethoxy)-5-methylpyridin-2-amine.

المصدر