تفاعل #926340

معادلة التفاعل

6-(3,4-methylenedioxyphenyl)-3-hexenyl iodide

lithium

3,5-heptanedione

→

4-[6-(3,4-Methylenedioxyphenyl)-3-hexenyl]-3,5-heptanedione

المذيبات

dimethylformamide

ظروف التفاعل

المعالجة

1. 1
   أخرىwas prepared from 12.5 g
2. 2
   أخرىThe product was chromatographed on silica gel
3. 3
   غسيلeluted with pentane-benzene (1:1)

الإجراء التجريبي

[I; Ar is 3,4-methylenedioxyphenyl, R0 is H, R' and R" are CH3CH2CO, Y is CH=CHCH2CH2 ] was prepared from 12.5 g. of 6-(3,4-methylenedioxyphenyl)-3-hexenyl iodide (Preparation D2) and 12.5 g. of the lithium salt of 3,5-heptanedione in 175 ml. of dimethylformamide. The product was chromatographed on silica gel and eluted with pentane-benzene (1:1) and then with chloroform-benzene (7:3). The latter brought out 7.0 g. of 4-[6-(3,4-methylenedioxyphenyl)-3-hexenyl]-3,5-heptanedione as a light amber oil.

المصدر