تفاعل #91963

معادلة التفاعل

3-methyl-4-[(2-methylpropan-2-yl)oxycarbonyl]morpholine-3-carboxylic acid

trifluoroacetic acid

→

3-methylmorpholine-3-carboxylic acid

المذيبات

DCM

ظروف التفاعل

المعالجة

1. 1
   تركيزconcentrated under the vacuum
2. 2
   أخرىThe residue was used directly in next step without further purification

الإجراء التجريبي

To a solution of 3-methyl-4-[(2-methylpropan-2-yl)oxycarbonyl]morpholine-3-carboxylic acid (Accela ChemBio Co., Ltd., CAS: 1052680-53-1, 50 mg, 0.2.0 mmol) in DCM (1 ml) was added trifluoroacetic acid (1 mL) dropwise at room temperature. The resulting mixture was stirred at room temperature for one hour and then concentrated under the vacuum. The residue was used directly in next step without further purification,

المصدر