تفاعل #91267

معادلة التفاعل

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine

(6-hydroxy-7-methyl-benzofuran-3-yl)-acetic acid methyl ester

→

title compound

المردود 83.9%

[6-(2-cyclopentylsulfanyl-pyridin-3-ylmethoxy)-7-methyl-benzofuran-3-yl]-acetic acid

المردود 83.9%

ظروف التفاعل

المعالجة

1. 1
   أخرىobtained in Preparation Example 54
2. 2
   أخرىto react sequentially in the same manner as in Steps A and B of Example 1

الإجراء التجريبي

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine (21 mg, 0.09 mmol) obtained in Step C of Preparation Example 8 and (6-hydroxy-7-methyl-benzofuran-3-yl)-acetic acid methyl ester (21 mg, 0.09 mmol) obtained in Preparation Example 54 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (30 mg, 83%).

المصدر