تفاعل #91263

معادلة التفاعل

2-Chloromethyl-6-isopropylsulfanyl-pyridine

2-(4-hydroxy-2,3-dimethyl-phenyl)-cyclopropane carboxylic acid ethyl ester

→

title compound

المردود 83.1%

2-[4-(6-isopropylsulfanyl-pyridin-2-ylmethoxy)-2,3-dimethyl-phenyl]-cyclopropane carboxylic acid

المردود 83.1%

ظروف التفاعل

المعالجة

1. 1
   أخرىto react sequentially in the same manner as in Steps A and B of Example 1

الإجراء التجريبي

2-Chloromethyl-6-isopropylsulfanyl-pyridine (0.030 g, 0.149 mmol) obtained in Step C of Preparation Example 16 and 2-(4-hydroxy-2,3-dimethyl-phenyl)-cyclopropane carboxylic acid ethyl ester (0.035 g, 0.149 mmol) obtained in Step C of Preparation Example 48 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.046 g, 83%).

المصدر