تفاعل #91180

معادلة التفاعل

2-(4-benzyloxy-3,5-difluoro-phenyl)-cyclopropanecarboxylic acid

SOCl2

→

title compound

2-(4-benzyloxy-3,5-difluoro-phenyl)-cyclopropanecarbonyl chloride

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONwas added
2. 2
   أخرىAfter the termination of the reaction
3. 3
   تركيزthe reactant was concentrated under reduced pressure

الإجراء التجريبي

After 2-(4-benzyloxy-3,5-difluoro-phenyl)-cyclopropanecarboxylic acid (75 mg, 0.246 mmol) was dissolved in anhydrous MC (5 ml), SOCl2 (0.58 g, 4.92 mmol) was added thereto, and the mixture was stirred at room temperature for 18 hours. After the termination of the reaction, the reactant was concentrated under reduced pressure to obtain the title compound, which was used in the next step without a separate purification process.

المصدر