تفاعل #89604

معادلة التفاعل

3,4-Dimethyl-pentanal

Dibutylamine

acetic acid

formaldehyde

→

3,4-dimethyl-2-methylene-pentanal

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   workup.WAITaged for another hour
2. 2
   درجة الحرارةThe reaction mixture was cooled down
3. 3
   غسيلThe reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L)

الإجراء التجريبي

Dibutylamine (34 g), acetic acid (15.78 g), and formaldehyde (230 g) were charged to a reaction flask and heated to 70° C. 3,4-Dimethyl-pentanal (500 g) was fed over 2 hours and aged for another hour. The reaction mixture was cooled down and toluene (200 mL) was added. The reaction mixture was sequentially washed with water (2 L), sodium carbonate solution (1 L), and brine (1 L) to provide the crude product 3,4-dimethyl-2-methylene-pentanal.

المصدر