تفاعل #89549

معادلة التفاعل

4-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid

2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione

2-chloro-5-(trifluoromethyl)pyridine

→

title compound

(4-Fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)((2S,3R)-3-methyl-2-(((5-(trifluoromethyl)pyridin-2-yl)amino)methyl)piperidin-1-yl)methanone

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared following the same general protocol as described in Example A318, using 4-fluoro-3-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid, 2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione and 2-chloro-5-(trifluoromethyl)pyridine. ESI-MS (m/z): 477 (M+H).

المصدر