تفاعل #89532

معادلة التفاعل

5-cyano-2-(2H-1,2,3-triazol-2-yl)benzoic acid

2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione

2-fluoro-5-(trifluoromethyl)pyrimidine

→

title compound

3-((2S,3R)-3-Methyl-2-(((5-(trifluoromethyl)pyrimidin-2-yl)amino)methyl)piperidine-1-carbonyl)-4-(2H-1,2,3-triazol-2-yl)benzonitrile

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared following the same general protocol as described in Example A1, using 5-cyano-2-(2H-1,2,3-triazol-2-yl)benzoic acid, 2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione and 2-fluoro-5-(trifluoromethyl)pyrimidine. ESI-MS (m/z): 471 [M+1]+.

المصدر