تفاعل #88122

معادلة التفاعل

1-(2,4-difluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

intermediate I

1-(2,4-difluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole

2-(4-fluoro-phenyl)-acetonitrile

→

title compound

5-[2-(2,4-Difluoro-phenyl)-2H-pyrazol-3-yl]-3-(4-fluoro-phenyl)-benzo[c]isoxazole

ظروف التفاعل

الإجراء التجريبي

The title compound, light grey solid (22 mg, 17%), MS (ISP) m/z=392.2 [(M+H)+], mp 149° C., was prepared in accordance with the general method of example 1 from 1-(2,4-difluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate I) (100 mg, 353 μmol) and commercially available 2-(4-fluoro-phenyl)-acetonitrile.

المصدر