تفاعل #8771
ord-f69e3581a28d42ec827522042311ea49
معادلة التفاعل
3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole
potassium carbonate
3-methoxybenzylamine
→
title compound
(3-methoxy-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine
المتفاعلات
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1غسيلis eluted with a graded solvent mixture of 50% ethyl acetate in heptane to 100% ethyl acetate
الإجراء التجريبي
The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 3-methoxybenzylamine and acetonitrile essentially as described above in example 35, except that the column is eluted with a graded solvent mixture of 50% ethyl acetate in heptane to 100% ethyl acetate. Purity by LC/MS (APCI)=99%, [M+H]+=381.