تفاعل #87294

معادلة التفاعل

4-(1-Oxoindan-2-ylidenemethyl)benzonitrile

N-bromosuccinimide

benzoyl peroxide

→

15a

4-(1-Bromo-3-oxoindan-2-ylidenemethyl)benzonitrile

المذيبات

carbon tetrachloride

ظروف التفاعل

المعالجة

1. 1
   أخرىReaction mixture
2. 2
   درجة الحرارةwas reflux for 9 h
3. 3
   درجة الحرارةcooled down
4. 4
   ترشيحprecipitate was filtered off
5. 5
   غسيلwashed with diethyl ether (10×30 mL) for removal of N-hydroxysuccinimide Precipitate
6. 6
   أخرىwas dried under vacuum

الإجراء التجريبي

4-(1-Oxoindan-2-ylidenemethyl)benzonitrile (2.18 g, 8.9 mmol) was dissolved in carbon tetrachloride (40 mL). N-bromosuccinimide (1.58 g, 8.9 mmol) and benzoyl peroxide (100 mg) were added in one portion. Reaction mixture was reflux for 9 h, cooled down; precipitate was filtered off and washed with diethyl ether (10×30 mL) for removal of N-hydroxysuccinimide Precipitate was dried under vacuum, provided pure 15a.

المصدر