تفاعل #86049

ord-c5f12971cb8a4f7694030a941dd2f8a3

معادلة التفاعل

Nc1nc2c(-c3cccc(C(F)(F)F)c3)cccn2n1
8-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
COc1ccc(B(O)O)cc1
4-methoxyphenyl boronic acid
COc1ccc(-c2cccn3nc(N)nc23)cc1
8-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Made by following the procedure described for the preparation of 8-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine with 4-methoxyphenyl boronic acid and making non-critical variations.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US09434732B2uspto-grants-2016_09