تفاعل #85873

معادلة التفاعل

2-(oxiran-2-ylmethyl)isoindoline-1,3-dione

dibenzylamine

→

solid

المردود 56.2%

2-(3-(dibenzylamino)-2-hydroxypropyl)isoindoline-1,3-dione

المردود 56.2%

المذيبات

EtOH

ظروف التفاعل

المعالجة

1. 1
   workup.STIRRINGstirred at room temperature
2. 2
   ترشيحThe mixture was filtered

الإجراء التجريبي

A mixture of 2-(oxiran-2-ylmethyl)isoindoline-1,3-dione (4.06 g, 20.0 mmol) and dibenzylamine (5.0 g, 25.4 mmol) was stirred at 80° C. overnight. EtOH (50 mL) was added, and stirred at room temperature. The mixture was filtered to give white solid (4.5 g).

المصدر