تفاعل #85672

معادلة التفاعل

(S)-tert-butyl 1-(3-fluoro-4-formylphenyl)ethylcarbamate

4,4-difluoropiperidine hydrochloride

intermediate 111

aluminum

→

Title compound

(S)-tert-butyl 1-(4-((4,4-difluoropiperidin-1-yl)methyl)-3-fluorophenyl)ethylcarbamate

ظروف التفاعل

الإجراء التجريبي

Following the procedure for intermediate 111: Title compound was prepared from (S)-tert-butyl 1-(3-fluoro-4-formylphenyl)ethylcarbamate and 4,4-difluoropiperidine hydrochloride as a white solid. LCMS tR=1.63 min; MS m/z 371.5 (M−H).

المصدر