تفاعل #853

معادلة التفاعل

2,5-Dimethyl-p-phenylenediamine

benzoylisothiocyanate

→

colorless crystal

المردود 98.7%

1,4-di(benzoylthiocarbamoylamino)-2,5-dimethylbenzene

المردود 98.7%

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةAfter cooling
2. 2
   ترشيحthe reaction mixture was filtered
3. 3
   غسيلwashed with ethyl acetate/n-hexane

الإجراء التجريبي

2,5-Dimethyl-p-phenylenediamine (0.340 g, 2.5 mM) was dissolved in 30 ml of ethyl acetate, and 2 equivalents of benzoylisothiocyanate (0.816 g, 5 mM) were added. The mixture was stirred at room temperature for 10 minutes. After cooling, the reaction mixture was filtered, and washed with ethyl acetate/n-hexane to obtain 1.14 g (98.6% yield) of a colorless crystal of compound A-26.

المصدر