تفاعل #85241

معادلة التفاعل

methyl 4-({2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)-2-methylbenzoate

Methyl 4-({2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)-2-methylbenzoate

lithium hydroxide

→

4-({2-[4-(5-Chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)-2-methylbenzoic acid

ظروف التفاعل

الإجراء التجريبي

120 mg (0.27 mmol) of methyl 4-({2-[4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]propanoyl}amino)-2-methylbenzoate (racemate) (Example 2.6A) were hydrolysed with lithium hydroxide according to General Method 3. Yield: 39 mg (purity 93%, 33% of theory)

المصدر