تفاعل #84727

معادلة التفاعل

(2-amino-5-bromo-3-chlorophenyl)methanol

→

title compound

المردود 91.0%

2-amino-5-bromo-3-chlorobenzaldehyde

المردود 91.0%

المذيبات

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe solid was filtered off
2. 2
   تركيزthe filtrate was concentrated

الإجراء التجريبي

A mixture of (2-amino-5-bromo-3-chlorophenyl)methanol (10.0 g, 42.5 mmol) and manganese oxide (21.9 g, 255 mmol) in dichloromethane (400 mL) was stirred at room temperature overnight. The solid was filtered off, and the filtrate was concentrated to give the title compound as a light yellow solid (9.0 g, 91%), which was directly used in the next step without further purification.

المصدر