تفاعل #83634

معادلة التفاعل

2-Fluorobenzaldehyde

malonitrile

→

2-Fluorobenzylidenemalonitrile

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe solution was heated
2. 2
   درجة الحرارةto reflux
3. 3
   أخرىOnce the vigorous reaction
4. 4
   درجة الحرارةthe solution was heated for 15 minutes
5. 5
   درجة الحرارةchilled
6. 6
   ترشيحCrystals of product were filtered off
7. 7
   غسيلwashed with ethanol, m.p. 122° C.

الإجراء التجريبي

2-Fluorobenzaldehyde (15.8 ml) was dissolved in ethanol (100 ml) and to the stirred solution was added malonitrile (9.9 g). The solution was heated to reflux, the heating discontinued and piperidine (4 drops) was added. Once the vigorous reaction had diminished, the solution was heated for 15 minutes and then chilled. Crystals of product were filtered off and washed with ethanol, m.p. 122° C.

المصدر