تفاعل #83451

معادلة التفاعل

7-chloro-10,11-dihydro-5H-imidazo[2,1-c][1,4]-benzodiazepine

4-[(2-methylbenzoyl)amino]benzoyl chloride

triethylamine

→

desired product

N-[4-(7-Chloro-5H-imidazo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl]phenyl]-2-methylbenzamide

المذيبات

dichloromethane

ظروف التفاعل

الإجراء التجريبي

As described for Example 125 a mixture of 1 mmol of 7-chloro-10,11-dihydro-5H-imidazo[2,1-c][1,4]-benzodiazepine, 1.1 mmol of 4-[(2-methylbenzoyl)amino]benzoyl chloride and 1.5 mmol of triethylamine in 10 ml of dichloromethane is stirred at room temperature for 3 hours and worked up to give the desired product as a solid.

المصدر