تفاعل #83175

معادلة التفاعل

D-glucono1,5-lactone

tallowaminopropylamine

→

D-gluconamide

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىA 1 liter round bottom flask equipped with a condenser, addition funnel
2. 2
   أخرىthe heating mantle removed
3. 3
   درجة الحرارةThe reaction mixture was cooled
4. 4
   ترشيحThe white product was filtered
5. 5
   غسيلwashed with cold isopropanol (3×100ml)
6. 6
   أخرىdried under vacuum at 35° C.

الإجراء التجريبي

A 1 liter round bottom flask equipped with a condenser, addition funnel, thermometer and mechanical stirrer was charged with D-glucono1,5-lactone (20.0 g, 0.11 mole) and methanol (56 g). The suspension was heated to 40° C. over 15 minutes and the heating mantle removed. Hydrogenated tallowaminopropylamine (36.0 g, 0.11 mole) was added dropwise over 15 minutes with rapid stirring. The reaction mixture was cooled and placed in a refrigerator at 0° C. overnight. The white product was filtered, washed with cold isopropanol (3×100ml) and dried under vacuum at 35° C. giving 46.2 g (83% yield) of hydrogenated tallowaminopropyl D-gluconamide with a melting point of 112°-115° C.

المصدر