تفاعل #81890

معادلة التفاعل

3,5-diacetylaniline

cyanoguanidine

HCl

→

N-(3,5-diacetylphenyl)biguanide hydrochloride

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةheated
2. 2
   درجة الحرارةat reflux
3. 3
   درجة الحرارةAfter 6 hr the mixture was cooled
4. 4
   تركيزconcentrated
5. 5
   ترشيح0.248 g of off-white solid was filtered out
6. 6
   أخرىdried

الإجراء التجريبي

Compound No. 12. A suspension of 3,5-diacetylaniline (0.531 g) in water (8 mL) was treated with cyanoguanidine (0.285 g) and conc. HCl (0.25 mL) and heated at reflux. After 6 hr the mixture was cooled and concentrated and 0.248 g of off-white solid was filtered out and dried to give N-(3,5-diacetylphenyl)biguanide hydrochloride, mp 260°-70° C. (dec).

المصدر