تفاعل #8152

معادلة التفاعل

2-chloro-5-nitropyridine

hydrazine hydrate

→

(5-nitropyridin-2-yl)hydrazine

المذيبات

ethanol

ethanol

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONAt the end of the addition
2. 2
   أخرىThe named product precipitated from the reaction medium
3. 3
   ترشيحwas collected by filtration
4. 4
   أخرىrecrystallized from ethanol

الإجراء التجريبي

To a solution of 2-chloro-5-nitropyridine (30 mmol, 5.0 g) in absolute ethanol was added a solution of hydrazine hydrate (320 mmol, 15.8 g) in ethanol using syringe pump. At the end of the addition, the reaction was refrigerated. The named product precipitated from the reaction medium, was collected by filtration, and recrystallized from ethanol.

المصدر