تفاعل #81043

ord-5aec6e135de84d3e8073ee25308a0747

الكواشف

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المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    استخلاصextracted with toluene
  2. 2
    أخرىThe organic phase is isolated
  3. 3
    تركيزconcentrated on a rotary evaporator
  4. 4
    أخرىto give, at 88°-92° C.

الإجراء التجريبي

A 750 ml flask is charged with 6.7 g (50 mmol) of anhydrous aluminium chloride and 120.2 g (1 mol) of mesitylene. 148.7 g (1 mol) of 1-chloroctane are added dropwise to this mixture over 2 h at room temperature. HCl gas slowly evolves. The dark orange emulsion is stirred for c. 30 h at room temperature and then poured into water and extracted with toluene. The organic phase is isolated and concentrated on a rotary evaporator. The resultant oil is fractionated under vacuum to give, at 88°-92° C. and 1.8 mbar, 80.6 g of the title product as a colourless liquid. Gas chromatography (GC) and 1H-NMR spectrum analysis show that mono-n-octylmesitylene is obtained in 90% purity. The distillation residue contains mainly dioctylmesitylene.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05616787uspto-grants-1997_04