تفاعل #80688

معادلة التفاعل

1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione

hydrogen

→

title product

1-(5-Amino-2-chloro-4-fluorophenyl)-3-methyl-s-triazine-2,4,6(1H,3H, 5H)-trione

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe reaction mixture is then filtered
2. 2
   تركيزconcentrated in vacuo

الإجراء التجريبي

A mixture of 1-(2-chloro-4-fluoro-5-nitrophenyl)-3-methyl-s-triazine-2,4,6(1H,3H,5H)-trione (28.5 g, 0.09 mol) and 5% platinum on activated carbon (1 g) in ethyl acetate is hydrogenated at 55 psi until hydrogen uptake is complete. The reaction mixture is then filtered and concentrated in vacuo to give the title product as a white solid, mp 244°-245° C.

المصدر