تفاعل #80380

ord-304f722ccc9a419a99f92f803e252f20

معادلة التفاعل

NC/C=C\COc1cc(CN2CCCCC2)ccn1
4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenylamine
O=C(Cl)CCCCCl
5-chlorovaleryl chloride
O=C(CCCCCl)NC/C=C\COc1cc(CN2CCCCC2)ccn1
title compound
المردود 93.0%
O=C(CCCCCl)NC/C=C\COc1cc(CN2CCCCC2)ccn1
N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-5-chloropentanamide
المردود 93.0%

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Following a procedure similar to that described in Example 67(a), but using 4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenylamine and 5-chlorovaleryl chloride as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as an oil in a 93% yield.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US05616579uspto-grants-1997_04