تفاعل #792146

معادلة التفاعل

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one

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title compound

المردود 59.6%

1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)propan-1-one

المردود 59.6%

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىto give a yellow solution
2. 2
   ترشيحThe reaction mixture was filtered
3. 3
   أخرىevaporated
4. 4
   غسيلthe solid residue was washed with diethylether
5. 5
   أخرىdried

الإجراء التجريبي

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

المصدر