تفاعل #790926

معادلة التفاعل

potassium hydroxide

ethylene glycol

3,4-methylenedioxynitrobenzene

→

2-hydroxy-4-nitrophenoxyethanol

ظروف التفاعل

المعالجة

1. 1
   أخرىbeing kept in the region of 100° C
2. 2
   درجة الحرارةAfter heating for two hours
3. 3
   أخرىThe expected product crystallizes in the form of the potassium phenate
4. 4
   ترشيحThe phenate is filtered off
5. 5
   workup.DISSOLUTIONredissolved in 250 ml of water
6. 6
   أخرىThe 2-hydroxy-4-nitrophenoxyethanol precipitates
7. 7
   ترشيحAfter filtration
8. 8
   غسيلwashing with water
9. 9
   أخرىdrying in vacuo

الإجراء التجريبي

0.2 mol (11.2 g) of potassium hydroxide is dissolved in 167 ml of ethylene glycol in a boiling water bath. 0.1 mol (16.7 g) of 3,4-methylenedioxynitrobenzene is added, with stirring, the temperature being kept in the region of 100° C. After heating for two hours, the reaction medium is cooled to -5° C. The expected product crystallizes in the form of the potassium phenate. The phenate is filtered off and then redissolved in 250 ml of water, and the solution is acidified to pH=6 with concentrated hydrochloric acid. The 2-hydroxy-4-nitrophenoxyethanol precipitates. After filtration, washing with water and drying in vacuo, the expected product melts at 158° C.

المصدر