تفاعل #7906

ord-7df2cf2c036f4ca89fda9641812f2c45

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىto give a colorless oil

الإجراء التجريبي

A solution of N′-{4-[1-(4-chlorophenyl)cyclobutyl]thiazol-2-yl}-N,N-diethylpropane-1,3-diamine, 19, (78.9 mg, 0.209 mmol) and citric acid (40.2 mg, 0.209 mmol) in methanol (10 mL) was concentrated to give a colorless oil. The oil was dissolved in water (10 mL) and lyophilized to give N′-{4-[1-(4-chlorophenyl)cyclobutyl]thiazol-2-yl}-N,N-diethylpropane-1,3-diamine citrate salt, 20, as a white powder.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07087623B2uspto-grants-2006_08