تفاعل #78803

معادلة التفاعل

DMF

o-aminothiophenol

Ac2O

→

compound ( A )

المردود 32.0%

indole

المردود 32.0%

المذيبات

benzene

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONThe reaction mixture was poured
2. 2
   ترشيحthe precipitated solid was collected by filtration
3. 3
   غسيلThe crude solid was washed with MeOH
4. 4
   أخرىrecrystallized from benzene

الإجراء التجريبي

A dry DMF solution of the compound (A-2) (0.01 mole) was added o-aminothiophenol (0.013 mole) and Ac2O (0.5ml) at room temperature. The mixture was stirred at 60° C. for 3 h. The reaction mixture was poured into stirred benzene and the precipitated solid was collected by filtration. The crude solid was washed with MeOH and recrystallized from benzene to afford target compound (A) (32% yield). 1H-NMR spectrum is shown in FIG. 3. Photoluminescence spectrum is shown in FIG. 4.

المصدر