تفاعل #78037

ord-d01a7072414048f0959f8877f8c7fd94

معادلة التفاعل

C[C@]12CCC(=O)C(Cl)=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)C[C@@H]3C[C@]312
4-Chloro-17β-hydroxy-14α,15α-methylene-androst-4-ene-3-one
Br
hydrobromic acid
→
C[C@]12CCC(=O)C(Br)=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)C[C@@H]3C[C@]312
4-Bromo-17β-hydroxy-14α,15α-methylene-androst-4-ene-3-one

المتفاعلات

C[C@]12CCC(=O)C(Cl)=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)C[C@@H]3C[C@]312
4-Chloro-17β-hydroxy-14α,15α-methylene-androst-4-ene-3-one
Br
hydrobromic acid

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The target compound is synthesized in a manner similar to the synthesis of 4-Chloro-17β-hydroxy-14α,15α-methylene-androst-4-ene-3-one, 48% hydrobromic acid being used instead of hydrochloric acid.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06710039B1uspto-grants-2004_03