تفاعل #78026

معادلة التفاعل

3,3′-dinitro-4,4′-diaminobiphenyl

2-furoyl chloride

hydrochloric acid

→

3,3′-dinitro-4,4′-di-2-furoylamino-biphenyl

المردود 81.2%

المذيبات

water

N,N-dimethylformamide

water

pyridine

ظروف التفاعل

المعالجة

1. 1
   أخرىIn a 500 ml separable flask equipped with a stirrer, a reflux condenser
2. 2
   workup.ADDITIONAfter the addition
3. 3
   درجة الحرارةthe reaction solution was warmed to the room temperature
4. 4
   أخرىthe solid substance was separated by filtration
5. 5
   غسيلThe obtained solid substance was washed well with water
6. 6
   أخرىdried in a reduced pressure

الإجراء التجريبي

In a 500 ml separable flask equipped with a stirrer, a reflux condenser cooled with water, a thermometer and a dropping funnel, 10.96 g of 3,3′-dinitro-4,4′-diaminobiphenyl was dissolved into 200 ml of N,N-dimethylformamide and then 20 ml of pyridine was added to the solution. While the prepared solution was cooled at 3 to 14° C., 12.53 g of 2-furoyl chloride was added dropwise to the solution. After the addition was completed, the reaction solution was warmed to the room temperature and stirred for further 5 hours. Then, 80 ml of 2N hydrochloric acid and 100 ml of water were added to the solution and the solid substance was separated by filtration. The obtained solid substance was washed well with water and dried in a reduced pressure to obtain 15.0 g of 3,3′-dinitro-4,4′-di-2-furoylamino-biphenyl. The yield was 81%.

المصدر