تفاعل #77373

ord-12f638ffe9e949e99e5e28a062188c8f

معادلة التفاعل

CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2c(c1)CC(=O)N2
2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-methyl-amide
O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde
→
CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2c(c1)C(=Cc1cc3cc(OCCN4CCCC4)ccc3[nH]1)C(=O)N2
title compound
CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2c(c1)C(=Cc1cc3cc(OCCN4CCCC4)ccc3[nH]1)C(=O)N2
2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid (3-cloro-phenyl)-methyl-amide

المتفاعلات

CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc2c(c1)CC(=O)N2
2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-methyl-amide
O=Cc1cc2cc(OCCN3CCCC3)ccc2[nH]1
5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-methyl-amide was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06706709B2uspto-grants-2004_03