تفاعل #76906

ord-3b7e3e2af5984c44bb297a13b305a6fa

معادلة التفاعل

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccc(F)cc1
4-fluorobenzylamine
COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccc(F)cc2)cc1OC
2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(4-fluoro-benzyl)-acetamide

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 4-fluorobenzylamine

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US06703392B2uspto-grants-2004_03