تفاعل #7666

معادلة التفاعل

N-[1-(3-cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclobutanecarboxamide

phosphoric trichloride

→

7-Cyclobutyl-2-cyclopentyl-5-ethylimidazo[5,1-f][1,2,4]triazin-4(3H)-one

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةat reflux for 3 hours

الإجراء التجريبي

In analogy to the procedure for Example 1, 270 mg (0.90 mmol) crude N-[1-(3-cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclobutanecarboxamide, 140 mg (0.90 mmol) phosphoric trichloride are stirred at reflux for 3 hours, proportionate amounts of the solvents are used.

المصدر