تفاعل #7647

معادلة التفاعل

6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one

2-methyl-cyclopropylcarbonyl chloride

→

N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-2-methylcyclopropanecarboxamide

ظروف التفاعل

المعالجة

1. 1
   أخرىThe crude product is used in the next step without further purification

الإجراء التجريبي

In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 90 mg (0.74 mmol) 2-methyl-cyclopropylcarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

المصدر