تفاعل #7641

ord-b46f015255f1488ebf4026b731b6fb22

معادلة التفاعل

CCC(N)c1nnc(C(C)(C)C)[nH]c1=O
6-(1-aminopropyl)-3-tert-butyl-1,2,4-triazin-5(4H)-one
O=C(Cl)C1CCCC1
cyclopentanecarbonyl chloride
CCC(NC(=O)C1CCCC1)c1nnc(C(C)(C)C)[nH]c1=O
N-[1-(3-tert-Butyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclopentanecarboxamide

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe crude product is used in the next step without further purification

الإجراء التجريبي

In analogy to the procedure for Example 36A, 110 mg (0.50 mmol) 6-(1-aminopropyl)-3-tert-butyl-1,2,4-triazin-5(4H)-one, 70 mg (0.50 mmol) cyclopentanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07087605B2uspto-grants-2006_08