تفاعل #76380

معادلة التفاعل

2-benzyloxy-6-bromomethyl-naphthalen

2-Benzyloxy-6-bromomethyl-naphthalen

triphenylphosphine

→

(6-Benzyloxynaphthalen-2-ylmethyl)-triphenyl-phosphonium Bromide

المردود 98.0%

المذيبات

DMF

ظروف التفاعل

المعالجة

1. 1
   أخرىquenched with ethyl acetate
2. 2
   ترشيحThe resulting white solid of (6-benzyloxynaphthalen-2-ylmethyl)-triphenylphosphonium bromide (19) was filtered
3. 3
   غسيلwashed with ethyl acetate

الإجراء التجريبي

The solution of 2-benzyloxy-6-bromomethyl-naphthalen (18) (1 equi.), and triphenylphosphine (1.1 equi.) in DMF (0.6 mL/mmole was stirred at 95 C for 15 h, cooled to room temperature, and quenched with ethyl acetate. The resulting white solid of (6-benzyloxynaphthalen-2-ylmethyl)-triphenylphosphonium bromide (19) was filtered and washed with ethyl acetate. Yield 98%.

المصدر