تفاعل #7636

ord-00d5b1f294a447d5b9529db33c3cae5a

معادلة التفاعل

CCC(N)c1nnc(-c2ccc(Br)cc2)[nH]c1=O
6-(1-aminopropyl)-3-(4-bromophenyl)-1,2,4-triazin-5(4H)-one
O=C(Cl)C1CCCC1
cyclopentanecarbonyl chloride
CCC(NC(=O)C1CCCC1)c1nnc(-c2ccc(Br)cc2)[nH]c1=O
N-{1-[3-(4-Bromophenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamide

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

In analogy to the procedure for Example 36A, 3.35 g (10.8 mmol) 6-(1-aminopropyl)-3-(4-bromophenyl)-1,2,4-triazin-5(4H)-one, 2.16 g (16.3 mmol) cyclopentanecarbonyl chloride and proportionate amounts of the other reagents are used.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US07087605B2uspto-grants-2006_08