تفاعل #7612

معادلة التفاعل

cyclohexylcarboxylic acid chloride

2-amino-pyridine

tert.-butylisonitrile

benzaldehyde

→

3-(tert-butyl-cyclohexancarbonyl-amino)-1-cyclohexancarbonyl-2-phenyl-imidazo[1,2-a]pyridin-1-ium chloride

المذيبات

perchloric acid

ظروف التفاعل

الإجراء التجريبي

Example 10 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) tert.-butylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process steps b) to d) by reacting the resultant reaction product with 0.4 mmol cyclohexylcarboxylic acid chloride.

المصدر