تفاعل #75393

ord-d0f3470974684dfab26c1ed77269735f

معادلة التفاعل

CC1(C)N=CC2=C3N=C(Cc4ccccc4)N=C3C(=O)CC2C1=O
7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
Cl.ClCCN1CCOCC1
2-morpholino-ethyl chloride hydrochloride
→
CC1(C)N=CC2=C3N=C(Cc4ccccc4)N=C3C(=O)C(CCN3CCOCC3)C2C1=O.Cl.Cl
7,7-Dimethyl-2-benzyl-5-(2-morpholino-ethyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

المتفاعلات

CC1(C)N=CC2=C3N=C(Cc4ccccc4)N=C3C(=O)CC2C1=O
7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
Cl.ClCCN1CCOCC1
2-morpholino-ethyl chloride hydrochloride

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

Prepared analogous to Example 23 from 1.6 gm of 7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione and 1.2 gm of 2-morpholino-ethyl chloride hydrochloride.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04176184uspto-grants-1979_11