تفاعل #75218

معادلة التفاعل

sodium glyoxylate

ammonium acetate

phenol

→

DL-p-hydroxyphenylglycine

المردود 50.4%

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONare added
2. 2
   workup.STIRRINGThe mixture is stirred at 30° to 35° C. for 48 hours
3. 3
   أخرىAfter the reaction
4. 4
   أخرىthe crystalline precipitates
5. 5
   ترشيحare collected by filtration
6. 6
   درجة الحرارةunder cooling
7. 7
   غسيلsuccessively washed with water and methanol

الإجراء التجريبي

36.9 g of sodium glyoxylate are added to 130 ml of water, and 75 g of ammonium acetate and 60 g of phenol are added thereto under stirring. The mixture is stirred at 30° to 35° C. for 48 hours. After the reaction, the crystalline precipitates are collected by filtration under cooling, and then successively washed with water and methanol. 27.2 g of DL-p-hydroxyphenylglycine are thereby obtained as white crystals.

المصدر