تفاعل #74880

معادلة التفاعل

stearic acid chloride

sorbitol

hydrochloric acid

→

sorbitol stearate

المذيبات

toluene

pyridine

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONare added dropwise to this mixture over 25 minutes
2. 2
   أخرى(at approx. 110° C.)
3. 3
   أخرىfor 1 hour
4. 4
   درجة الحرارةunder reflux
5. 5
   درجة الحرارةAfter cooling
6. 6
   غسيلis then washed with water until neutral and
7. 7
   تجفيفdried with dehydrated sodium sulphate
8. 8
   أخرىAfter concentration of the organic phase the sorbitol stearate crystallizes
9. 9
   أخرىIt is recrystallized from methanol

الإجراء التجريبي

411.5 g (1.358 mols) stearic acid chloride are dissolved in 3 l toluene and heated to 90° C. 41.23 g (0.22 mols) of sorbitol, dissolved in 200 ml pyridine are added dropwise to this mixture over 25 minutes. The solution is boiled (at approx. 110° C.) for 1 hour under reflux. After cooling, dilute hydrochloric acid is added to acidify the mixture, which is then washed with water until neutral and dried with dehydrated sodium sulphate. After concentration of the organic phase the sorbitol stearate crystallizes. It is recrystallized from methanol.

المصدر