تفاعل #7431

معادلة التفاعل

2′,3′-difluoro-4′-ethoxybiphenylboronic acid

1-bromo-3-fluoro-4-iodobenzene

triphenylphosphine

sodium carbonate

→

terphenyl

المذيبات

isopropanol

water

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةrefluxed overnight

الإجراء التجريبي

0.047 mol of 2′,3′-difluoro-4′-ethoxybiphenylboronic acid (14), 0.05 mol of 1-bromo-3-fluoro-4-iodobenzene (15), 1 mmol of palladium acetate, 2 mmol of triphenylphosphine, 25 ml of saturated sodium carbonate solution, 20 ml of water and 100 ml of isopropanol are initially introduced and refluxed overnight. Conventional work-up gives the terphenyl compound (16).

المصدر