تفاعل #742252

معادلة التفاعل

3-(2-hydroxy-phenyl)-acrylic acid ethyl ester

dec-9-en-1-ol

→

colourless crystals

المردود 21.5%

(E)-3-(2-Hydroxy-phenyl)-acrylic acid dec-9-enyl ester

المردود 21.5%

المذيبات

ether

ظروف التفاعل

المعالجة

1. 1
   أخرىremoving the ethanol
2. 2
   أخرىformed
3. 3
   درجة الحرارةthe reaction mixture was cooled
4. 4
   غسيلwashed with brine
5. 5
   أخرىThe organic phase was dried
6. 6
   أخرىevaporated to dryness
7. 7
   workup.DISTILLATIONThe resulting oil was Kugelrohr-distilled
8. 8
   أخرىcrystallized
9. 9
   أخرىrecrystallized

الإجراء التجريبي

A mixture of 5.0 g 3-(2-hydroxy-phenyl)-acrylic acid ethyl ester, 6.1 g dec-9-en-1-ol and 1.0 g tetraisopropyl-ortho-titanate was heated to 150° C. removing the ethanol formed. After stirring for 2.5 hours at this temperature, the reaction mixture was cooled, diluted with ether and washed with brine. The organic phase was dried and evaporated to dryness. The resulting oil was Kugelrohr-distilled, crystallized and recrystallized to yield 1.69 g of colourless crystals.

المصدر