تفاعل #742248

معادلة التفاعل

(E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid

citronellol

p-toluene-sulfonic acid

water

→

colourless oil

(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 3,7 dimethyl-oct-6-enyl ester

المذيبات

cyclohexane

hexane

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThen the reaction mixture was cooled down
2. 2
   غسيلwashed
3. 3
   أخرىThe organic phase was dried
4. 4
   ترشيحfiltered
5. 5
   أخرىevaporated to dryness
6. 6
   أخرىThe resulting yellow oil was purified by chromatography

الإجراء التجريبي

A solution of 6 0 g of (E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid, 5.3 g of citronellol and 1 g of p-toluene-sulfonic acid in 150 ml of cyclohexane was refluxed for 6.5 hours using a water separator. Then the reaction mixture was cooled down, diluted with hexane and washed to neutrality with saturated sodium bicarbonate and water. The organic phase was dried, filtered and evaporated to dryness. The resulting yellow oil was purified by chromatography to yield 6.45 g of a colourless oil.

المصدر