تفاعل #739630

معادلة التفاعل

5-acetyl-1H-indole-3-ethanamine

phthalic anhydride

sodium acetate

→

title compound

2-[2-(5-Acetyl-1H-indol-3-yl)ethyl]-1H-isoindole-1,3(2H)-dione

المذيبات

acetic acid

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas heated
2. 2
   درجة الحرارةat reflux for 3 h

الإجراء التجريبي

A suspension of 5-acetyl-1H-indole-3-ethanamine (1.0 g), phthalic anhydride (0.83 g) and sodium acetate (1.0 g) in acetic acid (15 ml) was heated at reflux for 3 h. On cooling the title compound was deposited as an off-white crystalline solid (1.5 g) m.p. 234°-5°.

المصدر