تفاعل #73611

معادلة التفاعل

cyclopentanecarbonyl chloride

2-amino-4-methylthiazole-5-carboxylic acid benzylamide

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title compound

المردود 38.0%

2-(Cyclopentanecarbonylamino)-4-methylthiazole-5-carboxylic Acid Benzylamide

المردود 38.0%

ظروف التفاعل

الإجراء التجريبي

Following the procedure as described in Example 2, making variations only as required to use cyclopentanecarbonyl chloride in place of benzoyl chloride to react with 2-amino-4-methylthiazole-5-carboxylic acid benzylamide, the title compound was obtained as a white solid in 38% yield; 1H NMR (CDCl3, 300 MHz) δ 9.56 (s, br, 1H), 7.35-7.24 (m, 5H), 5.92 (s, br, 1H), 4.56 (d, J=5.7 Hz, 2H), 2.81-2.69 (m, 1H), 2.62 (s, 3H), 1.97-1.72 (m, 8H); MS (ES+) m/z 344.2 (M+1).

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