تفاعل #73163

معادلة التفاعل

Intermediate B

(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one

5-fluoro-2-(1H-imidazol-2-yl)pyridine

→

title compound

(R)-8-cyclopentyl-7-ethyl-2-(2-(5-fluoropyridin-2-yl)-1H-imidazol-1-yl)-5-methyl-7,8-dihydropteridin-6(5H)-one

ظروف التفاعل

الإجراء التجريبي

The title compound was prepared similarly to the methods described in Example 77, with Intermediate B instead of Intermediate C and with 5-fluoro-2-(1H-imidazol-2-yl)pyridine instead of 2-phenyl-1H-imidazole. LCMS: 422.3 m/z (M+H)+; ret. Time: 6.73 min (Analytical Method C).

المصدر